Abstract
Cardiovascular diseases are the leading cause of mortality and morbidity in the Czech Republic. The primary objective in reducing their risk, lowering LDL cholesterol and, consequently, increase HDL cholesterol.
Therapy of choice is a complex therapy, including pharmacotherapy and lifestyle measures (diet, physical activity). Nowadays, we can increase the value of HDL cholesterol by about 20 %.
Perhaps in the near future drugs will become avaiable that increase the lench of HDL cholesterol by up to 100 %.