Fibroblast Growth Factor 21: A Novel Metabolic Regulator With Potential Therapeutic Properties in Obesity/Type 2 Diabetes Mellitus

Abstract

Fibroblast growth factor 21 (FGF21) is a novel metabolic regulator produced primarily by the liver that exerts potent antidiabetic and lipid-lowering effects in animal models of obesity and type 2 diabetes mellitus.

Keywords

• Fibroblast growth factor 21
• fasting
• obesity
• type 2 diabetes
• peroxisome proliferator-activated receptor
• glucose uptake