Increased serum concentrations of macrophage inhibitory cytokine-1 in patients with obesity and type 2 diabetes mellitus: the influence of very low calorie diet

Abstract

Macrophage inhibitory cytokine-1 (MIC-1) is a novel regulator of energy homeostasis. We explored whether alterations in MIC-1 levels contribute to metabolic disturbances in patients with obesity and/or obesity and type 2 diabetes mellitus (T2DM).

Keywords

• TGF-beta superfamily
• gene-expression
• adipose tissue
• member
• MIC-1
• activation
• anorexia
• profile
• plasma
• injury