Publication at First Faculty of Medicine |
2009
Abstract
The determination of biomarkers in saliva has become an important part of laboratory diagnostics and prediction of diseases concerning periodontium as well as other organs. Salivary biomarkers (e.g. enzymes, protein markers or markers of oxidative stress) may serve for the determination of activity as well as prognosis of periodontium diseases.
Saliva also contains a series of markers which make it possible top predict the risk of some general diseases (e.g. diabetes mellitus, cardiovascular, oncological, endocrinological or psychiatric diseases). The proteomic study of salivary components makes it clear that there is an association between periodontium disease and changed general state of health, diseases of remote systems or organs.
Keywords
saliva periodontal fluid detection of periodontium inflammation determination of activity of periodontium diseases salivary markers determination of CRP in saliva salivary fibronectin aspartate aminotransferase nitrogen oxide radical oxidative stress detection of drugs in saliva oncological depistage