CYSL-1 Interacts with the O-2-Sensing Hydroxylase EGL-9 to Promote H2S-Modulated Hypoxia-Induced Behavioral Plasticity in C. elegans

Abstract

This study shows a novel role for the nematode enzyme cysteine synthase (CYSL-1) in the signaling cascade of HIF-1 in response to hypoxia

Keywords

• o-acetylserine sulfhydrylase
• cystathionine beta-synthase
• caenorhabditis-elegans
• hydrogen-sulfide
• inducible factor
• serine acetyltransferase
• guanylate cyclases
• active-site
• oxygen
• cysteine