Polymorphisms in Serotonin-Related Genes in Anorexia Nervosa. The First Study in Czech Population and Meta-analyses with Previously Performed Studies

Abstract

Anorexia nervosa is a serious psychiatric disorder characterized by the inability to maintain normal body weight. Results of this study support previous reports of a significant role of the A allele (-1438A/G, 5-HT2A receptor) as a risk factor in anorexia nervosa.

Keywords

• Anorexia nervosa
• gene polymorphisms
• serotonin
• meta-analysis
• Czech population
• promoter polymorphism
• 5-ht2a receptor
• transporter gene
• bulimia-nervosa
• eating-disorders
• association
• obesity
• susceptibility
• mortality
• variants