Dokovací doména histonu H2A je nezbytná pro navázání histonu H1 a remodelaci nukleozomu pomocí RSC

Abstrakt

Using biochemical methods in combination with Atomic Force Microscopy and Electron Cryo-Microscopy, we show that the H2A-docking domain is a key structural feature within the nucleosome.

Klíčová slova

• chromatin
• nucleosome
• transcription factor
• core particle
• DNA