Abstract
The significance of vitamin D for human health is usually reduced to its necessity for correct skeletogenesis in the period of growth and for the optimal mineralisation of bone tissue in adults. However, the level of saturation by vitamin D might play an important role in the risk of cardiovascular, malignant, autoimmune and some infection diseases.
The mystery of vitamin D is hidden in its transformation to its active form, calcitriol, which interacts with its nuclear receptor and influences the expression of more than 500 genes of human genome.