Histopathological autoptic findings in 8 patients with pandemic influenza A (H1N1) pneumonia

Abstract

In the years 2009 and 2010 a novel influenza A(H1N1) caused the first influenza pandemic after 41 years. Here we report 8 autoptic cases of patients who died between 2009 and 2011 with confirmed H1N1 influeza and underwent a post mortem examination at the Institute of Pathology, General University Hospital an Prague, Czech Republic.

All 8 patients developed atypical pneumonia with sebsequent respiratory failure. In this article we present these cases with related clinical data and findings in other studies and case reports.

Keywords

• influenza A virus, subtype H1N1
• viral pneumonia
• diffuse alveolar damge