Denosumab: fast inhibition and fast reversibility of osteoclast function and safety and efficacy in the elderly

Abstract

Large clinical trials showed denosumab significantly reduced the risk of new vertebral and hip fractures in subgroups of women at high risk for these fractures. These results highlight the consistent antifracture efficacy of denosumab in patients with varying degrees of fracture risk.

Keywords

• denosumab
• bone resorption
• fracture
• bone mineral