Anti-tau antibodies in patients with multiple sclerosis. From pathogenesis to therapy of autoimmune diseases

Abstract

The presence of IgG antibodies against tau protein in serum and cerebrospinal fluid is not a specific phenomenon for multiple sclerosis. However, the increased anti-tau antibody index suggests an enhanced intrathecal humoral component interacting with neurocytoskeleton in patients with multiple sclerosis.

Keywords

• multiple sclerosis
• tau
• antibody
• cerebrospinal fluid
• serum