Tau protein determination in cerebrospinal fluid in patients with multiple sclerosis by two ELISA kits

Abstract

Tau protein belongs to the neuro-cytoskeletal proteins. Its concentration increases in the cerebrospinal fluid (CSF) due to the axonal damage.

The aim of the study was to examine the CSF levels of total tau protein in the patients with multiple sclerosis (MS) and others neurological diseases and to compare two ELISA kits for the tau determination.

Keywords

• tau protein
• multiple sclerosis
• ELISA
• cerebrospinal fluid