The OV-TL 12/30 Clone of Anti-cytokeratin 7 Antibody as a New Marker of Corneal Conjunctivalization in Patients with Limbal Stem Cell Deficiency

Abstract

The aim of our study was to show that cytokeratin (CK) 7 (OV-TL 12/30 clone) is a new, reliable marker for distinguishing between the conjunctival and corneal surface epithelia. The detection of CK7 (OV-TL 12/30 clone) clearly confirms the overgrowth of the conjunctival epithelium over the cornea.

CK7 appears to be a more reliable marker compared to CK19.

Keywords

• intermediate-filament expression
• impression cytology
• epithelial maintenance
• ocular surfaces
• human-eye
• transplantation
• phenotype
• keratin-7
• pathology
• patterns