Effect of polychlorinated biphenyls (PCBs) and 1,1,1-trichloro-2,2,-bis (4-chlorophenyl)-ethane (DDT) in follicular fluid on the results of in vitro fertilization embryo transfer (IVF-ET) programs

Abstract

Objective: To establish the effect of chlorinated organic compounds on fertility. We analyzed the influence of polychlorinated biphenyls (PCBs) and pesticides in follicular fluid on the number of fertilized oocytes, the quality of oocytes and embryos, pregnancy rate, and number of embryos cryoconserved in IVF-ET program.

Keywords

• DDD
• DDE
• DDT
• embryos
• oocytes
• PCB
• pregnancy rate
• menstrual-cycle characteristics
• sperm chromatin integrity
• organochlorine compounds
• endocrine disruptors
• serum ddt
• exposure
• placenta
• estrogen
• androgen
• antiandrogens