Peptide-steroids chimeras synthesis and visualization of their binding to the rat brain slices

Abstract

Oxytocin and its fragments have the potential to influence behavioral and cognitive functions. Therefore, there is an interest to synthesize new peptide-steroids chimeras for potential therapeutic use.The sites of the peptide-steroids chimeras bound to the brain tissue were identified with the aid of fluorescent microscopy. were identified with the aid of fluorescent microscopy.

Keywords

• oxytocin
• chimeras
• steroid-peptide
• imunofluroscence
• CNS