Hypervariable intronic region in NCX1 is enriched in short insertion-deletion polymorphisms and showed association with cardiovascular traits

Abstract

The study revealed in a muliethnic cohort that intronic variation in the Na+ (Ca2+) exchanger NCX1 is associated with an increased risk of coronary artery disease.

Keywords

• coronary-artery-disease
• human genetic-disease
• dna-sequence complexity
• molecular determinants
• metabolic syndrome
• hiv-1 infection
• receptor gene
• exchanger
• variants
• isoforms