Non invasive prenatal diagnostics of most frequent chromosomal aneuploidies in the language of numbers

Abstract

Practical possibilities of non-invasive prenatal diagnostics of Down syndrome based on examination of cell-free fetal DNA circulating in maternal plasma applied on non selected populacion and on patients with screening based indication for invasive examination are discussed.

Keywords

• non-invasive prenatal diagnostics
• cell-free DNA
• Down syndrome
• positive predictive value of the test