Publication at First Faculty of Medicine |
2010
Abstract
A 2-year-old asymptomatic boy and his relatives were investigated for a suspected fibrinogen mutation after coagulation tests revealed a decreased functional fibrinogen level (family A). Eight-year-old and 1-year-old asymptomatic brothers were investigated for a suspected fibrinogen mutation after coagulation tests revealed a decreased functional fibrinogen level and prolonged thrombin time (family B).
To identify whether genetic mutations were responsible for these dysfibrinogens, DNA extracted from the blood was analyzed.