Effect of fluoxetine or adenosine receptor NECA agonist on G-proteins of C6 glioma cells or NK immunocytes

Abstract

We studied the effect of acute administration of fluoxetine or NECA agonist of adenosine receptor (GPCR) on C6 glioma cells and natural killer (NK) cell line, innate immunity. We used immunochemical estimation (ELISA) of the main types of G-protein alpha subunits from isolated membranes of tested cells.

Keywords

• C6 glioma cells
• NK cells
• 1,4,5 IP3
• fluoxetine
• astrocyte
• trimeric GTP binding protein