Hybrid nanospheres formed by intermixed double-hydrophilic block copolymer poly(ethylene oxide)-block-poly(2-ethyloxazoline) with high content of metallacarboranes
2013
Abstract
In search for biocompatible hydrophilic polymers suitable for preparation of delivery systems of boron cluster compounds with high loading capacity, we studied the interaction of metallacarborane sodium [3-cobalt(III) bis(1,2-dicarbollide)] with poly(2-ethyloxazoline) (PEOX) and with a double-hydrophilic block copolymer poly(ethylene oxide)-block-poly(2-ethyloxazoline) (PEO–PEOX) in aqueous solutions by a combination of scattering, microscopy, spectroscopy, and thermochemistry techniques. The paper is a contribution to our long-time study of novel hybrid nanostructures based on hydrophilic polymer–metallacarborane complexes.