Cardiovascular Models : Heart Secondarily Affected by Disease

Abstrakt

Three experimental animal models are described and analysed. In these models the heart is not targeted primarily,but the primary disease eventually afects the cardiovascular system significantly : diabetes mellitus,renal failure,and dysfunctional autonomicinnervation.

Rat models of these three conditions are described in detail,with special focus on methodological aspects and experimental results obtained in our laboratory.

Klíčová slova

• Animal model
• cardiovascular
• diabetes mellitus
• renal failure
• sympathectomy