Interaction of Anthocyanins with Drug-metabolizing and Antioxidant Enzymes

Abstract

The present review summarizes anthocyanin properties with emphasis on the antioxidant capacity and deals with the potential of anthocyanins to modulate phase I and II drug-metabolizing enzymes, transporters and antioxidant enzymes. The undesirable and/or beneficial outcomes of possible interactions of anthocyanins with drugs or industrial pollutants are also discussed.

Keywords

• Anthocyanins
• anthocyanin-drug interactions
• antioxidant enzymes
• chemoprevention
• drug-metabolizing enzymes
• modulation of enzymatic activity
• transporters