Prepubertal Girls With Turner Syndrome and Children With Isolated SHOX Deficiency Have Similar Bone Geometry at the Radius

Abstract

The similar bone geometry changes of the radius in TS and SHOX-D patients support the hypothesis that loss of 1 copy of SHOX is responsible for the radial bone phenotype associated with TS.

Keywords

• Turner syndrome
• SHOX deficiency
• Bone geometry
• Leri-Weill Dyschondrosteosis
• Idiopathic short stature
• Quantitative computed-tomography
• X-ray absorptiometry
• Mineral density
• Gene SHOX
• Proximal radius
• Growth failure
• Prevalence
• Fractures