Ga-68-labeling via metal-induced de-esterification of NOPO-peptides

Abstrakt

Efficient labeling of NOPO-esters and NOPO-Zn(II) complexes is combined with unprecedented selectivity of this chelator for 68Ga(3+). The reported techniques of transcomplexation and de-esterification broaden the current spectrum of labeling methods and open the field for new structures that can be considered as motifs in metalchelate design.

Klíčová slova

• Ga-68
• labeling