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Ga-68-labeling via metal-induced de-esterification of NOPO-peptides

Publication at Faculty of Science |
2013

Abstract

Efficient labeling of NOPO-esters and NOPO-Zn(II) complexes is combined with unprecedented selectivity of this chelator for 68Ga(3+). The reported techniques of transcomplexation and de-esterification broaden the current spectrum of labeling methods and open the field for new structures that can be considered as motifs in metalchelate design.