N-Acetylhexosamine triad in one molecule: Chemoenzymatic introduction of 2-acetamido-2-deoxy-β-D-galactopyranosyluronic acid residue into a complex oligosaccharide

Abstract

A complex trisaccharide beta-D-GalpNAcA-(1 -> 4)-beta-D-GlcpNAc-(1 -> 4)-D-ManpNAc (3) was prepared in a good yield (35%) in a transglycosylation reaction catalyzed by beta-N-acetylhexosaminidase from Talaromyces flavus using p-nitrophenyl 2-acetam

Keywords

• beta-N-acetylhexosaminidase
• Talaromyces flavus
• galactopyranosiduronic acid
• modified substrate
• natural killer cell
• transglycosylation
• galactose-oxidase
• animal lectins
• disaccharides
• antigen
• binding