Monitoring of dimethyl sulphate-induced N3-methyladenine, N7-methylguanine and O-6-methylguanine DNA adducts using reversed-phase high performance liquid chromatography and mass spectrometry

Abstract

Monitoring of dimethyl sulphate-induced N3-methyladenine, N7-methylguanine and O-6-methylguanine DNA adducts using reversed-phase high performance liquid chromatography and mass spectrometry

Keywords

• N3-methyladenine
• N7-methylguanine
• O-6-methylguanine
• DNA methylated adducts
• dimethyl sulphate
• HPLC
• LC-MS-ESI(+)
• p-32 postlabeling analysis
• methyl-n-nitrosourea
• white blood-cells
• styrene oxide
• 7-alkylguanine adducts
• electrochemical detection
• tobacco-smoke
• agents
• 7-methylguanine
• repair