Isolation and partial characterization of the adduct formed by 13-hydroxyellipticine with deoxyguanosine in DNA

Abstract

Isolation and partial characterization of the adduct formed by 13-hydroxyellipticine with deoxyguanosine in DNA

Keywords

• anticancer drug
• ellipticine
• 13-hydroxyellipticine
• DNA adducts
• HPLC
• anticancer drug ellipticine
• cytochromes p450
• binding
• cells
• bioactivation
• microsomes
• metabolism
• oxidation
• enzymes
• nadph