Ellipticine and benzo(a)pyrene increase their own metabolic activation via modulation of expression and enzymatic activity of cytochromes P450 1A1 and 1A2

Abstract

Ellipticine and benzo(a)pyrene increase their own metabolic activation via modulation of expression and enzymatic activity of cytochromes P450 1A1 and 1A2

Keywords

• benzo(a)pyrene
• ellipticine
• induction
• cytochromes P450
• NADPH:cytochrome P450 reductase
• HRN mice