Gadolinium(III) complexes as MRI contrast agents: Ligand design and properties of the complexes

Abstract

A review dealing with lanthanide(III) (especially gadolinium(III)) complexes and evaluating their structures in the solid state, thermodynamic and kinetic properties and relaxometric parameters influencing their utilization as contrast agents in MRI.

Keywords

• water exchange-rate
• human serum-albumin
• nephrogenic systemic fibrosis
• macrocyclic polyamino carboxylates
• DOTA-tetraamide complexes
• lanthanide ion complexes
• acid pendant arms
• Gd(III) complexes
• X-ray crystal
• magnetic-resonance