Unsymmetrically substituted side-bridged cyclam derivatives and their Cu(II) and Zn(II) complexes

Abstract

Ligands derived from piperazine-containing cyclam and having acetate or phosphorus pendant arms were synthesized. Copper(II) and zinc(II) complexes are similar to those of cyclams with analogous pendant arms.

Keywords

• in-vivo behavior
• tetraazamacrocyclic complexes
• copper(II) complexes
• 1,4,8,11-tetraazacyclotetradecane cyclam
• receptor antagonists
• kinetic inertness
• pendant arms
• stability
• crystal
• ligands