Formal Total Synthesis of (±)-Estrone and Zirconocene-Promoted Cyclization of 2-Fluoro-1,7-octadienes and Ru-Catalyzed Ring Closing metathesis.

Abstract

Development of new synthetic strategy for the preparation of estrone basd on the use of organometallic methodology

Keywords

• zirconium
• cyclization
• metathesis
• estrone
• steropids
• ruthenium