An efficient modification of ellipticine synthesis and preparation of 13-hydroxyellipticine

Abstract

A simple modification of a previously published ellipticine synthesis is reported, which decreases the reaction time and increases the yield and purity of the product.

Keywords

• anticancer drug ellipticine
• covalent DNA-adducts
• 6H-pyrido<4,3-b>carbazoles
• deoxyguanosine
• oxidation
• chemistry