The anticancer drug ellipticine is an inducer of rat NAD(P)H : Quinone oxidoreductase

Abstract

The antineoplastic agent ellipticine was investigated for its ability to induce the biotransformation enzyme NAD(P) H:quinone oxidoreductase (DT-diaphorase, EC 1.6.99.2) in male Wistar rats

Keywords

• NAD(P)H:quinone oxidoreductase
• enzyme induction
• anticancer drugs
• carcinogens
• metabolic activation
• ellipticine