Use of photoaffinity labeling for study of cytochromes P450, toxicologically important enzymes

Abstract

The N-(p-azidobenzyl)-N-methyl-p-aminophenethyl-amine, heterobifunctional compound was examined as a potential photolabile probe for mapping the access region of CYP3A6

Keywords

• cytochrome P450
• photoaffinity labeling
• access channel
• substrate binding