Structural insight into the Pharmacophore Pocket of Human Glutamate Carboxypeptidase II

Abstract

Crystal structure of glutamate carboxypeptidase II complexed with three glutamate mimetics.

Keywords

• LINKED ACIDIC DIPEPTIDASE
• ASPARTYL-L-GLUTAMATE
• THIOL-BASED INHIBITORS
• N-ACETYLASPARTYLGLUTAMATE
• BIOLOGICAL EVALUATION
• MEMBRANE ANTIGEN
• QUISQUALIC ACID
• RAT-BRAIN
• ELECTRON-DENSITY
• NAALADASE