Study of thermodynamic and kinetic stability of transition metal and lanthanide complexes of DTPA analogues with a phosphorus acid pendant arm

Abstract

Dissociation constants of phosphonic and phenylphosphinic acid derivatives of DTPA and stability constants of their metal ion complexes were determined. Kinetic inertness of their gadolinium(III) complexes was investigated.

Keywords

• phosphonate complexes
• phosphinate complexes
• MRI contrast agents
• kinetics
• thermodynamics