Abstract
Diabetes mellitus is the leading cause of nontraumatic lower extremity amputation. Foot ulcers and infections are also a major source of morbidity in individuals with diabetes mellitus.
The reasons for the increased incidence of these disorders in diabetes mellitus involve the interaction of several pathogenic factors: neuropathy, abnormal foot biomechanics, peripheral arterial disease, and poor wound healing. These risk factors are summed in patients with syndrome of diabetic foot.