This paper presents the work program of Kurt Krolop Research Centre for German-Bohemian literature at Charles University in Prague. In addition to the current state of research and the theoretical foundations of the new approach of the research he focuses on the following nominated areas of research: "The era of liberalism", "Young Prague and the spring generation", "Franz Kafka", "The diversity of the Jewish: Between tradition, assimilation and modernity","Prague between Vienna, Berlin and Paris "," The cultural construct of the region" and "Literature - Culture models - Politics ".