Abstract
Aim of the study was to evaluate plasma levels of markers of structural myocardial damage in patients with hypertrophic cardiomyopathy (HCM). 21 pts with HCM was enrolled into the study. Echo and catheterization were performed before enrolment into the study.
We analyzed plasma troponin I (cTnI), troponin T (TnT), creatine kinase MB concentration (CK-MB), glycogenphosphorylase BB (GPBB), heart fatty acid binding protein (hFABP) and myoglobin (myo) levels. Compare to control group, plasma levels all evaluated parameters were significantly increased. Furthermore, we observed correlation between left ventricle mass and its index with plasma GPBB level.
While plasma troponin I level reached the cut-off limit for detection of myocardial injury in 5 patients, plasma troponin T level reached detection limit only in 1 patient. Our study found increase of plasma markers of structural myocardial damage (cTnI, GPBB, CK-MB, hFABP and myoglobin)....