Evaluation of in vitro protection by salicylaldehyde isonicotinoyl hydrazone (SIH) against hydrogen peroxide-and anthracycline-induced toxicity to cardiac cells

Abstrakt

In this study it was revealed that although iron chelator SIH can afford significant cardioprotection against both anthracycline cardiotoxicity and model oxidative stress, there are some limitations which can be among other associated with certain instability of the compound in biological fluids.