Abstract
The aim of this study was to elucidate functional cerebral changes in patients suffering from Neuroborreliosis and to compare the results with findings in clinically definite Multiple Sclerosis (MS). In 39 patients with MS and 100 patients with Neuroborreliosis we investigated two types of visual evoked potentials (VEPs) - the pattern-reversal VEPs (R-VEPs) and the motion-onset VEPs (M-VEPs). 25 MS patients exhibited pathological results in R-VEPs (prolonged latency of the main P100 peak), which was accompanied by prolonged latency of the M-VEPs (N160 peak) in 14 cases. 46 patients with Neuroborreliosis exhibited prolonged latency of the M-VEPs, which was accompanied by prolonged latencies of the R-VEPs in 14 cases only.
Our study supports the concept of functional damage of the visual pathway in Neuroborreliosis but in contrast to MS the Neuroborreliosis seems to affect predominantly the magnocellular system and/or the dorsal stream.