Publication at Central Library of Charles University, Faculty of Medicine in Hradec Králové |
2004
Abstract
Potential organ toxicity after repeated administration of novel iron chelator - pyridoxal 2-chlorobenzoyl hydrazone (o-108) - was preliminarily assessed in rabbits. Histological examination did not reveal any distinct organ damage.
Thus o-108 remains promising iron chelator from the standpoint of its potential therapeutic use.