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Multidrug resistance markers monitoring in acute myeloid leukemia cells

Publication at Central Library of Charles University, Faculty of Medicine in Hradec Králové |
2004

Abstract

Laboratory methods to detect markers of multiple drug resistance P-gp, MRP, LRP and markers of apoptosis, Bcl-2 and Bax were established. The correlation between the percentage of blasts and expression of MDR and Bcl-2 together with correlation between the expression of MRP and Bax and LRP and Bax was found.