Publication at Faculty of Medicine in Hradec Králové |
2004
Abstract
The recent neuropsychological research has emphasized memory deficit as one of a key area of impairment in schizophrenia. Evidence is accumulating that these impairments are predominantly related to abnormalities in the prefrontal cortex and mediotemporal structures of the brain.
Some authors consider the memory dysfunction as a selective deficit in patients with schizophrenia. Cognitive impairments, particularly information processing and working memory have proven to be strongest predictors of overall social functioning and quality of life of patients with schizophrenia.