Abstract
Hemostatic (hemostyptic) biomaterials - oxidized cellulose with their ability to initiate or accelerate thrombus formation belong to surgical sealants. Platelets in plasma but not washed platelets in a buffer were activated in the presence of cellulose.
We suppose that activation of the coagulation contact system of blood plasma initiated very likely by the negatively charged surface of the oxidized cellulose leads to the fibrin formation and activation and adhesion of blood platelets.