Abstrakt
The aim of the experimental study is to find out how fibrin influences the speed of osteointegration of bioactive glass-ceramic materials BAS-O,BAS-HA,BAS-R. Dense materials BAS-O (glass-ceramics),BAS-HA(hydroxyapatite) nad BAS-R (beta tricalcium phosphate)in the form of 0,6-1 mm granules were implanted in articially created defects in tibia of an experimental animal with the addition of 0,1 ml fibrin adhesive system Beriplast.Radiographs of materials with the fibrin system showed clearly after one week defects and implants, after the third week part of the materials penetrated above the bone surface, after the fourth week evident sings of bone tissue formation between particles of BAS-HA,BAS-R and their mixtures.The most marked bone formation took place in the seventh and eighth weeks.
With the use of glass-ceramics without fibrin the particles were three weeks less clear, after fourth BAS-HA and BAS-R penetrated above the surface.A significant bone formation was obvious after the sixth and seventh weeks. There were no sings of resorption of fibrous encapsulating.
Small differences with the use of fibrin were andjusted within six weeks. Materials BAS-HA,BAS-R and their mixtures were completely osteointegrated.Glass-ceramics BAS-O was partially enveloped by fibrous tissue, even with the use of fibrin adhesive system.