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Type 2 diabetes mellitus and bone

Publication at First Faculty of Medicine |
2013

Abstract

Diabetes mellitus and osteoporotic fractures are important causes of morbidity and mortality in elderly patients. Recently published studies have confirmed an increased risk of hip fractures and vertebral fractures in type 1 and also type 2 diabetes when compared to the healthy population.

The etiopathogenic link between these chronic diseases is poorly understood. Increased bone fragility in pa - tients with diabetes mellitus is caused by many factors such as advanced glycation end products, abnormal renal function, changes in insulin levels or the influence of some antidiabetic drugs.

This article gives an overview of risk factors for developing bone metabolism disorders in patients with type 2 diabetes.