Abstract
Treatment of the rectal adenocarcinoma is multidisciplinary. Radiotherapy is the important component of the treatment.
Neoadjuvant chemoradiotherapy is indicated in tumours T3-4 or in the case of positive lymph nodes. 5-fluorouracil and capecitabine are the most used cytostatics in combination with radiotherapy. The aim of the neoadjuvant treatment circumferential radial margin (CRM) after total mesorectal excision (TME).