Publication at First Faculty of Medicine |
2013
Abstract
Article comment on a recent article published in Brain by Hacker et al. (2012), which reported functional connectivity alteration in 13 patients with Parkinson's disease in the medicated state compared with healthy control subjects. Although the authors showed very interesting results, they colud not disentangle the effects of levodopa within the patient group.
Authors in this article investigated the influence of dopaminergic medication on patients with Parkinson's disease in an in an intra-individual design based on functional connectivicity derived from resting state functional MRI.